Arch. Dis. Child

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER


[Advanced]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this link to a friend
Right arrow Similar articles in ADC Online
Right arrow Similar articles in PubMed
Right arrow Add article to my folders
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dimitriou, G
Right arrow Articles by Milner, A D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dimitriou, G
Right arrow Articles by Milner, A D
Arch Dis Child Fetal Neonatal Ed 1998;78:F148-F150 ( March )

Volume delivery during high frequency oscillation

G Dimitriou,a A Greenough,a V Kavvadia,a B Laubscher,a A D Milnerb

a Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, b Department of Paediatrics, United Medical and Dental Schools, St Thomas' Hospital, London

Correspondence to: Professor A Greenough, Children Nationwide Regional Neonatal Intensive Care Centre, 4th floor, Ruskin Wing, King's College Hospital, London SE5 9RS.


Accepted 24 September 1997

AIM---To examine the delivered volume during "high volume strategy" high frequency oscillation, used as rescue treatment in preterm infants; and to identify factors, other than frequency and oscillatory amplitude, influencing the magnitude of volume delivery.
METHOD---Twenty infants (median gestational age 29 weeks) were studied on 45 occasions. Two oscillator types were used (SensorMedics and SLE). Delivered volume was measured under clinical conditions with the arterial blood gases within a predetermined range. A specially calibrated pneumotachograph system was used.
RESULTS---Overall, the median delivered volume was 2.4 ml/kg (range 1.0 to 3.6 ml/kg); on 32 occasions the delivered volume was greater than 2.0 ml/kg and on seven greater than 3.0 ml/kg. The delivered volume related significantly to disease severity; there was an inverse correlation between delivered volume and both the oxygenation index (OI) (r=-0.51) and AaDO2 (r=-0.54).
CONCLUSION---Delivered volume during HFO may, in certain infants, exceed the anatomical dead space, permitting some direct alveolar ventilation.

Keywords: high frequency oscillation; prematurity; delivered volume

© 1998 by Archives of Disease in Childhood


This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
G. DASSIEU, L. BROCHARD, M. BENANI, S. AVENEL, and C. DANAN
Continuous Tracheal Gas Insufflation in Preterm Infants with Hyaline Membrane Disease . A Prospective Randomized Trial
Am. J. Respir. Crit. Care Med., September 1, 2000; 162(3): 826 - 831.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER
ARCH DIS CHILD FETAL NEONATAL ED ED PRACTICE
Terms and conditions relating to subscriptions purchased online  ¦  Website terms and conditions  ¦  Privacy policy
Copyright © 1998 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health