Nasal high frequency ventilation in neonates with moderate respiratory insufficiency
Department of
Neonatology, Academic Hospital Maastricht, P
Debyelaan 25 PO Box 5800 6202 AZ Maastricht, The
Netherlands.
Correspondence to: Dr Mark van der Hoeven. Email: MVH{at}SKIN.AZM.NL
Accepted 14 January
1998
AIM
To investigate the
efficacy of nasal high frequency ventilation (nHFV) in newborn infants
with moderate respiratory insufficiency.
METHODTwenty
one preterm and term neonates were treated with nHFV for respiratory
insufficiency. Criteria for starting nHFV were: deterioration on nasal
CPAP expressed by a median pH of 7.24 and pCO2 of 8.3 kPa,
or increasing FIO2. nHFV was delivered using the Infant
Star ventilator. Ventilator setting amplitude was 35 cm
H2O; mean airway pressure 7 cm H2O; and
frequency 10 Hz.
RESULTSpCO2
decreased significantly from 8.3 kPa to 7.2 kPa after nHFV was started.
In five patients nHFV was discontinued after a median period of
61/2 hours due to CO2 retention
and high oxygen need, and endotracheal mechanical ventilation was started.
CONCLUSIONSnHFV can
reduce pCO2 in neonates with moderate respiratory
insufficiency and, therefore, could be used to decrease the need for
endotracheal mechanical ventilation.
© 1998 by Archives of Disease in Childhood
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