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Arch Dis Child Fetal Neonatal Ed 1999;80:F64-F68 ( January )

Outbreak of extended spectrum beta  lactamase producing Klebsiella pneumoniae in a neonatal unit

Jennifer Royle,a Sharon Halasz,b Gillian Eagles,b Gwendolyn Gilbert,b Dianne Dalton,a Peter Jelfs,c David Isaacsa

a Department of Immunology and Infectious Diseases, Royal Alexandra Hospital for Children, PO Box 3515 Parramatta NSW 2124 Australia, b Department of Microbiology, c Department of Microbiology Westmead Hospital Westmead

Correspondence to: Associate Professor David Isaacs. Email: davidi{at}nch.edu.au


Accepted 6 August 1998

An outbreak of extended spectrum beta  lactamase producing Klebsiella pneumoniae (ESBLKp) in a neonatal unit was controlled using simple measures. Normally, the control of such infections can be time consuming and expensive. Seven cases of septicaemia resulted in two deaths. ESBLKp isolates were subtyped by pulsed field gel electrophoresis, and four of the five isolates typed were identical. Control of the outbreak was achieved by altered empiric antibiotic treatment for late onset sepsis and prevention of cross infection by strict attention to hand washing. Widespread colonisation of babies in the unit was presumed, so initial surveillance cultures were not performed. No further episodes of sepsis occurred.

Keywords: beta lactamase producing Klebsiella pneumoniae; antibiotic resistance; hygiene; sepsis


© 1999 by Archives of Disease in Childhood



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