Outbreak of extended spectrum 
lactamase producing
Klebsiella pneumoniae in a neonatal unit
a Department of Immunology and Infectious Diseases,
Royal Alexandra Hospital for Children, PO Box 3515 Parramatta NSW 2124 Australia, b Department of Microbiology, c Department
of Microbiology Westmead Hospital Westmead
Correspondence to: Associate Professor David Isaacs. Email: davidi{at}nch.edu.au
Accepted 6 August 1998
An outbreak of extended spectrum 
lactamase producing
Klebsiella pneumoniae (ESBLKp) in a neonatal unit was
controlled using simple measures. Normally, the control of such
infections can be time consuming and expensive. Seven cases of
septicaemia resulted in two deaths. ESBLKp isolates were subtyped by
pulsed field gel electrophoresis, and four of the five isolates typed
were identical. Control of the outbreak was achieved by altered empiric
antibiotic treatment for late onset sepsis and prevention of cross
infection by strict attention to hand washing. Widespread colonisation
of babies in the unit was presumed, so initial surveillance cultures were not performed. No further episodes of sepsis occurred.
lactamase producing Klebsiella pneumoniae;
antibiotic resistance;
hygiene;
sepsis
© 1999 by Archives of Disease in Childhood
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