Register for email alerts and news feeds:
This journal | BMJ Group
rss
Archives of Disease in Childhood - Fetal and Neonatal Edition 1999;80:F64-F68; doi:10.1136/fn.80.1.F64
Copyright © 1999 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Arch Dis Child Fetal Neonatal Ed 1999;80:F64-F68 ( January )

Outbreak of extended spectrum beta  lactamase producing Klebsiella pneumoniae in a neonatal unit

Jennifer Royle,a Sharon Halasz,b Gillian Eagles,b Gwendolyn Gilbert,b Dianne Dalton,a Peter Jelfs,c David Isaacsa

a Department of Immunology and Infectious Diseases, Royal Alexandra Hospital for Children, PO Box 3515 Parramatta NSW 2124 Australia, b Department of Microbiology, c Department of Microbiology Westmead Hospital Westmead

Correspondence to: Associate Professor David Isaacs. Email: davidi{at}nch.edu.au


Accepted 6 August 1998

An outbreak of extended spectrum beta  lactamase producing Klebsiella pneumoniae (ESBLKp) in a neonatal unit was controlled using simple measures. Normally, the control of such infections can be time consuming and expensive. Seven cases of septicaemia resulted in two deaths. ESBLKp isolates were subtyped by pulsed field gel electrophoresis, and four of the five isolates typed were identical. Control of the outbreak was achieved by altered empiric antibiotic treatment for late onset sepsis and prevention of cross infection by strict attention to hand washing. Widespread colonisation of babies in the unit was presumed, so initial surveillance cultures were not performed. No further episodes of sepsis occurred.

Keywords: beta lactamase producing Klebsiella pneumoniae; antibiotic resistance; hygiene; sepsis


© 1999 by Archives of Disease in Childhood

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

This article has been cited by other articles:

  • Isaacs, D (2006). Unnatural selection: reducing antibiotic resistance in neonatal units. Arch. Dis. Child. Fetal Neonatal Ed. 91: F72-F74 [Abstract] [Full Text]  
  • Sahloff, E. G., Martin, S. J. (2002). Extended-Spectrum {beta}-Lactamase Resistance in the ICU. Journal of Pharmacy Practice 15: 96-105 [Abstract]  
  • ISAACS, D. (2000). Rationing antibiotic use in neonatal units. Arch. Dis. Child. Fetal Neonatal Ed. 82: 1F-2 [Full Text]  

This Article

Services
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Latest from ADC

 

ADC is co-owned by the RCPCH and is the official journal of the European Academy of Paediatrics

BMJ Careers - Latest Paediatrics and Paediatric Surgery Jobs

Paediatrics and Paediatric Surgery Jobs