Effect of caffeine on neonatal splanchnic blood flow
a Department
of Neonatology, Jessop Hospital for Women,
Leavygreave Road,
Sheffield S3 7RE, b Department of Biomedical Science,
University of Sheffield, c Department of Medical Physics,
Leicester Royal Infirmary
Correspondence to: Dr Robert Coombs.
Accepted 13 August
1998
Doppler ultrasound was used to study the effect of the first
intravenous dose of caffeine on splanchnic haemodynamics in preterm neonates. Peak systolic velocity in the superior mesenteric artery and
coeliac axis was significantly reduced for 6 hours after caffeine infusion.
The effect of this reduction in blood flow to the neonatal
gut is not known.
© 1999 by Archives of Disease in Childhood
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