Mortality from early onset group B streptococcal infection in the United Kingdom
Newcastle Neonatal
Service Royal Victoria Infirmary
Newcastle upon Tyne NE1 4LP
Correspondence to: Dr N D Embleton. Email N.D.Embleton{at}newcastle.ac.uk
Accepted 16 October
1998
AIMS
To assess the
assumption that group B streptococcal infection is less common in the
United Kingdom than it is in the United States.
METHODSAll stillbirth
and neonatal death records in the former Northern Health Region were
scrutinised to determine how many babies had died of infection in
1981-96, and what had been the cause.
RESULTSFifty one of
630 206 live born babies had died of confirmed group B streptococcal
infection after becoming symptomatic within 48 hours of birth (0.8 neonatal deaths per 10 000 live births). There were a further 27 deaths
from infection without a confirmed microbiological diagnosis, and 17 stillbirths from confirmed group B streptococcal infection.
CONCLUSIONSThe
incidence of death from early onset infection was marginally higher
than the officially estimated rate for the United States before
widespread prophylaxis was attempted. Strategies for perinatal
prevention deserve greater attention in the United Kingdom.
© 1999 by Archives of Disease in Childhood
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