Continuous neonatal blood gas monitoring using a multiparameter intra-arterial sensor
a Neonatal
Intensive Care Unit, St James's University Hospital, Leeds, b All Saint's Hospital,
Chatham, Kent, c Rosie Maternity Unit, Addenbrooke's Hospital,
Cambridge, d Diametrics
Medical Ltd, High Wycombe, Bucks
Correspondence to: Dr S J Newell, Neonatal Intensive Care Unit, St James's University Hospital, Leeds LS9 7TF.
Accepted 16 October
1998
AIMS
To compare
arterial blood gas (ABG) readings obtained with a multiparameter
intra-arterial sensor with those from an ABG analyser.
METHODSAn MPIAS with
the ability to measure continuously pH, PaCO2, and
PaO2 was introduced via an umbilical arterial catheter in 27 neonates requiring intensive care. They underwent 3260 hours of
MPIAS monitoring, during which 753 ABG readings were performed.
RESULTSOverall bias
(mean difference: MPIAS-ABG) and precision (standard deviation of
differences) values were: 
0.002 and 0.022, respectively, for pH;
+0.26 and 0.52 for PaCO2 (kPa); and 0.19 and 0.99 for
PaO2 (kPa). This gave 95% limits of agreement as: 0.047
to +0.042 for pH, 0.76 to +1.28 kPa for PaCO2, and
2.13 to +1.75 kPa for PaO2. For each variable, precision
across readings from the same individual was better than overall
precision for all data. No complications related to the use of the
catheter were observed.
CONCLUSIONSContinuous
MPIAS ABG monitoring is an exciting development, with the potential to
reduce blood transfusions and improve ABG homeostasis.
© 1999 by Archives of Disease in Childhood
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