Body composition of preterm infants during infancy
a Special Care Baby
Unit Royal Victoria Infirmary
Newcastle upon Tyne, b Regional
Medical Physics Department Freeman Hospital
Newcastle upon Tyne, c Nutrition Department
Nutricia Ltd Trowbridge
Wiltshire
Correspondence to: Dr R J Cooke Ward 35, Leaze's Wing Royal Victoria Infirmary Newcastle upon Tyne NE1 4LP Email: R.J.Cooke{at}ncl.ac.uk
Accepted 14 November
1998
AIMS
To examine body
composition in preterm infants.
METHODSBody composition was
measured by dual energy x-ray
absorptiometry (DEXA) at hospital discharge, term, 12 weeks, and at 6 and 12 months corrected age in 125 infants (birthweight 
1750 g, gestational age 34 weeks).
RESULTSBody weight
derived by DEXA accurately predicted that determined by conventional
scales. In both sexes lean mass (LM), fat mass (FM), %FM, bone area
(BA), bone mineral mass (BMM), and bone mineral density (BMD) increased
rapidly during the study; significant changes were detectable between
discharge and term. At 12 months, LM, BA, and BMM, but not FM, %FM, or
BMD were greater in boys than in girls. Corrected for age, LM was less
than those of the reference term infant; FM
and %FM were similar; BMM was greater. Corrected for weight, LM was
similar to those of the reference infant, while the FM and %FM of
study infants were slightly greater.
CONCLUSIONSDEXA
accurately measures body mass. Body composition in preterm boys and
girls differs. Interpretation of DEXA values may depend on whether age
or body weight are regarded as the appropriate reference.
Keywords: body composition; dual emission energy x-ray absorptiometry; preterm
© 1999 by Archives of Disease in Childhood
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