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a Neonatal Nutrition
Research Group Royal Victoria Infirmary
University of Newcastle-upon-Tyne, b Department
of Haematology
Correspondence to: Dr Ian J Griffin Section of Neonatology Department of Pediatrics Baylor College of Medicine One Baylor Plaza Houston TX 77030 USA. Email:igriffin{at}neo.bcm.tmc.edu
Accepted 14 February
1999
AIMS
To prospectively
evaluate the iron nutritional status of preterm infants fed either a
term (0.5 mg/dl iron) or preterm (0.9 mg/dl) formulas fortified with
iron after hospital discharge.
METHODSHealthy
low birthweight preterm infants were randomly assigned into three
groups at the time of hospital discharge. Group A were fed an iron
fortified preterm formula (0.9 mg/dl iron) until 6 months corrected
age; group B, a fortified term formula (0.5 mg/l iron) until 6 months
corrected age group C, the preterm formula between hospital discharge
and term, then the term formula until 6 months corrected age.
RESULTSSeventy
eight infants were followed up to 6 months corrected age. Iron intake
from formula differed significantly between the groups (A, 1.17 mg/kg/day (SD 0.32) > C, 0.86 mg/kg/day (SD 0.40) = B, 0.81 mg/kg/day
(SD 0.23); p < 0.0001). Haemoglobin concentrations were similar to
those of iron sufficient preterm infants of the same postnatal age, and
term infants of the same postmenstrual age (after 3 months of age).
There were no significant differences in haemoglobin concentration (p = 0.391), plasma ferritin (A vs B, p = 0.322),
or in the incidence of iron deficiency (A vs
B, p = 0.534).
CONCLUSIONSIron
fortified formulas containing between 0.5 and 0.9 mg/dl iron seem to
meet the iron nutritional needs of preterm infants after hospital discharge.
This article has been cited by other articles:
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  K. E. Elizabeth, V. Krishnan, and P. Zachariah Auxologic, Biochemical and Clinical (ABC) Profile of Low Birth Weight Babies A 2-year Prospective Study J Trop Pediatr, December 1, 2007; 53(6): 374 - 382. [Abstract] [Full Text] [PDF]
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 L D Marriott, K D Foote, J A Bishop, A C Kimber, and J B Morgan Weaning preterm infants: a randomised controlled trial Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2003; 88(4): F302 - F307. [Abstract] [Full Text] [PDF]
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 K D Foote and L D Marriott Weaning of infants Arch. Dis. Child., June 1, 2003; 88(6): 488 - 492. [Abstract] [Full Text] [PDF]
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I J Griffin, M M Reid, K P B McCormick, and R J Cooke Zinc protoporphyrin/haem ratio and plasma ferritin in preterm infants Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2002; 87(1): F49 - 51. [Abstract] [Full Text] [PDF]
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D. G Sweet, G. A Savage, R. Tubman, T. R J Lappin, and H. L Halliday Cord blood transferrin receptors to assess fetal iron status Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2001; 85(1): F46 - 48. [Abstract] [Full Text] [PDF]
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D G Sweet, G Savage, T R J Tubman, T R J Lappin, and H L Halliday Study of maternal influences on fetal iron status at term using cord blood transferrin receptors Arch. Dis. Child. Fetal Neonatal Ed., January 1, 2001; 84(1): 40F - 43. [Abstract] [Full Text]
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