Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia
Giovanni Cionia, Barbara Bertuccellia, Antonio Boldrinib, Raffaello Canapicchia c, Barbara Fazzia, Andrea Guzzettaa, Eugenio Mercurid
a Stella Maris
Scientific Institute, Division of Child Neurology and Psychiatry, Via
dei Giacinti 2, I-56018 Calambrone, Pisa, Italy, b Neonatal Intensive Care Unit,
University of Pisa, c Department
of Neuroradiology, S Chiara Hospital, Pisa, Italy, d Department
of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith
Hospital, London, UK
Correspondence to: Dr Cioni email: ciono{at}inpe.unipi.it
Accepted 13 August 1999
AIM
To evaluate the
correlation between visual function and neurodevelopmental outcome in
children with periventricular leucomalacia at 1 and 3 years.
METHODVisual acuity,
visual field, ocular motility, and optokinetic nystagmus were tested in
29 infants with periventricular leucomalacia by brain magnetic
resonance imaging. All infants also had a structured neurological
examination and a Griffiths developmental assessment.
RESULTS21 of the
infants showed at least one abnormality of visual function. The degree
of visual impairmentthat is, the number of visual tests showing
abnormal resultscorrelated well with the results on developmental
assessment at both ages.
CONCLUSIONMultivariate
analysis showed that visual impairment was the most important
variable in determining the neurodevelopmental scores of these infants,
more than their motor disability and the extent of their lesions on
magnetic resonance imaging.
Keywords: vision; developmental score; magnetic resonance imaging; periventricular leucomalacia
© 2000 by Archives of Disease in Childhood
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
Atkinson, J, Braddick, O, Anker, S, Nardini, M, Birtles, D, Rutherford, M A, Mercuri, E, Dyet, L E, Edwards, A D, Cowan, F M
(2008). Cortical vision, MRI and developmental outcome in preterm infants. Arch. Dis. Child. Fetal Neonatal Ed.
93: F292-F297
[Abstract] [Full Text] -
Bassi, L., Ricci, D., Volzone, A., Allsop, J. M., Srinivasan, L., Pai, A., Ribes, C., Ramenghi, L. A., Mercuri, E., Mosca, F., Edwards, A. D., Cowan, F. M., Rutherford, M. A., Counsell, S. J.
(2008). Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent age. Brain
131: 573-582
[Abstract] [Full Text]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in ADC Online
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
