Oxygen saturation during the first 24 hours of life
L M O'Briena, V A Stebbensa, C F Poetsb, E G Heycocka, D P Southalla
a Academic Department
of Paediatrics, North Staffordshire Hospital, Stoke on Trent ST4
6QG, UK, b Department of Pediatric
Pulmonology, University of Hannover Medical School, Hannover, Germany
Correspondence to: Professor Southall email: cai_uk{at}compuserve.com
Accepted 28 November
1999
AIM
To determine
normative data for arterial oxygen saturation, measured by pulse
oximetry (SpO2), in healthy full term infants throughout
their first 24 hours of life.
METHODSLong term
recordings of SpO2, pulse waveform, and breathing movements
were made on 90 infants. Recordings were analysed for baseline
SpO2, episodes of desaturation
(SpO2 
80%), apnoeic pauses of 
four seconds, and
periodic apnoea ( three apnoeic pauses, each separated by 19 breaths).
RESULTSMedian
baseline SpO2 was 98.3% (range 88.7-100). Longitudinal
analysis at four hour intervals showed that SpO2 remained
stable until 20-24 hours of age, when it became significantly lower
(p < 0.03). Episodic desaturations were identified in 23 recordings. Nine prolonged desaturations (SpO2 80% for 20
seconds) were identified in six recordings. Four desaturations fell to
60%. Periodic apnoea was identified in 60% of recordings.
CONCLUSIONThe range
of SpO2 during the first 24 hours of life is similar to
that found previously during the first month of life. The clinical
significance of the prolonged episodes of desaturation observed
justifies further investigation.
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Key messages
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Keywords: pulse oximetry; neonate; oxygen saturation; apnoea
© 2000 by Archives of Disease in Childhood
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