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Archives of Disease in Childhood - Fetal and Neonatal Edition 2000;83:F143-F147; doi:10.1136/fn.83.2.F143
Copyright © 2000 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Arch Dis Child Fetal Neonatal Ed 2000;83:F143-F147 ( September )

Skin conductance and the stress response from heel stick in preterm infants

H Storm

Department of Paediatric Research and Section on Neonatalogy, Department of Paediatrics, The National Hospital, Oslo, Norway

Correspondence to: Dr Storm email: hanne.storm{at}klinmed.uio.no

Accepted 17 May 2000

AIM---To evaluate whether spontaneous skin conductance activity is an objective method for measuring the stress response to painful stimuli in premature infants. The number and amplitude of the waves and the baseline increase with the activity of the sympathetic nervous system.
METHODS---In 20 preterm infants of gestational age >=  29 weeks, behavioural state and spontaneous skin conductance activity variables were measured for three minutes before, during, and for three minutes after heel stick.
RESULTS---The number of waves (p < 0.001), the amplitude of the waves (p = 0.001), and the level of the behavioural state (p < 0.001) increased during heel stick, and then decreased to levels found before the procedure. The baseline increased both during (p < 0.001) and after heel stick (p < 0.001), compared with levels before.
CONCLUSION---Spontaneous skin conductance activity reflects the stress response to heel stick in premature infants from at least 29 weeks of gestational age.


Key messages

  • Measurements of spontaneous skin conductance activity showed stress responses to heel stick from at least 29 weeks gestational age in healthy premature infants
  • The number and amplitude of the waves of spontaneous skin conductance activity mirror the response of the sympathetic nervous system to the emotional state
  • Monitoring skin conductance activity variables may be a useful tool for surveying stress responses to pain stimuli in premature infants. The method is easy to use, and artefacts occur only if the electrodes become detached from the skin




Keywords: arousal; heel stick; premature infants; skin conductance activity; stress; pain


© 2000 by Archives of Disease in Childhood

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This article has been cited by other articles:

  • Gjerstad, A. C., Wagner, K., Henrichsen, T., Storm, H. (2008). Skin Conductance Versus the Modified COMFORT Sedation Score as a Measure of Discomfort in Artificially Ventilated Children. Pediatrics 122: e848-e853 [Abstract] [Full Text]  

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