Resonance frequency in respiratory distress syndrome
S Lee, A D Milner
Newborn Respiratory
Unit, Department of Paediatrics, 4th floor, North Wing, St Thomas'
Hospital, London SE1 7EH, UK
Correspondence to: Prof. Milner email: anthony.milner{at}kcl.ac.uk
Accepted 28 April
2000
AIM
To observe how the resonance
frequency changes with the course of respiratory distress syndrome
(RDS), by examining the effect of changing static compliance on the
resonance frequency in premature infants.
METHODSIn 12 ventilated premature
infants with RDS (mean gestational age 26.6 weeks, mean birth weight
0.84 kg), resonance frequency and static compliance were determined
serially using phase analysis and single breath mechanics technique
respectively in the first seven days of life.
RESULTSThe minimum number of
measurements done in any one baby was three and maximum was five in
this seven day study period. The first measurement in each baby was
done within the first 72 hours of life. The increase in compliance in
this period varied from 27% to 179%. The variation in the
corresponding resonance frequency was within 2 Hz in eight babies and
within 6 Hz in all recruited babies.
CONCLUSIONSThe resonance frequency
of the respiratory system in preterm infants with RDS remains
remarkably constant in the early stages of the illness, despite
relatively large changes in static compliance.
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Key messages
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Keywords: resonance frequency; respiratory distress syndrome; high frequency oscillation; compliance
© 2000 by Archives of Disease in Childhood
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