Arch. Dis. Child

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER


[Advanced]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Read responses to this article
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this link to a friend
Right arrow Similar articles in ADC Online
Right arrow Similar articles in PubMed
Right arrow Add article to my folders
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hacking, D
Right arrow Articles by Nolan, T
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hacking, D
Right arrow Articles by Nolan, T
Arch Dis Child Fetal Neonatal Ed 2001;84:F117-F121 ( March )

Respiratory distress syndrome and birth order in premature twins

D Hackinga, A Watkinsa, S Frasera, R Wolfeb, T Nolanb, on behalf of Australia and New Zealand Neonatal Network

a Department of Paediatrics, Mercy Hospital for Women, Clarendon Street, East Melbourne, Victoria 3002, Australia, b Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Melbourne, Victoria 3052, Australia

Correspondence to: Dr Hacking, International Child Health Group, Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK doug.hacking{at}imm.ox.ac.uk

Accepted 12 November 2000

OBJECTIVE---To determine the effect of birth order on respiratory distress syndrome (RDS) in the outcome of twins in a large premature population managed in a modern neonatal intensive care unit.
METHODS---An historical cohort study design was used to analyse the neonatal outcomes of 301 premature liveborn twin sibling pairs of between 23 and 31 weeks gestation from the Australia and New Zealand Neonatal Network 1995 database.
RESULTS---Among the 56 twin sibling pairs who were discordant for RDS, the second twin was affected in 41 cases (odds ratio (OR) 2.7, 95% confidence interval (CI) 1.5 to 5.3). The excess risk of RDS in the second twin increased with gestation and was statistically significant for twins above 29 weeks gestation (OR 4.4, 95% CI 1.6 to 15).
CONCLUSIONS---There is a significant increased risk of RDS associated with being the second born of premature twins, which appears to depend on gestation.


Keywords: respiratory distress syndrome; twins; premature; birth order; gestation

© 2001 by Archives of Disease in Childhood


This article has been cited by other articles:


Home page
 Obstet GynecolHome page
B. A. Armson, C. O'Connell, V. Persad, K. S. Joseph, D. C. Young, and T. F. Baskett
Determinants of perinatal mortality and serious neonatal morbidity in the second twin.
Obstet. Gynecol., September 1, 2006; 108(3): 556 - 564.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
E S Shinwell, I Blickstein, A Lusky, and B Reichman
Effect of birth order on neonatal morbidity and mortality among very low birthweight twins: a population based study
Arch. Dis. Child. Fetal Neonatal Ed., March 1, 2004; 89(2): F145 - F148.
[Abstract] [Full Text] [PDF]

eLetters:

Read all eLetters

Birth order and RDS : Some controversy in the literature
N Naor
Fetal Neonatal Ed. Online, 20 Jul 2001 [Full text]
Re: Birth order and RDS : Some controversy in the literature
Doug Hacking
Fetal Neonatal Ed. Online, 26 Jul 2001 [Full text]

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER
ARCH DIS CHILD FETAL NEONATAL ED ED PRACTICE
Terms and conditions relating to subscriptions purchased online  ¦  Website terms and conditions  ¦  Privacy policy
Copyright © 2001 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health