The influence of congenital heart disease on survival of infants with oesophageal atresia
H Leonarda, A M Barrettb, J E S Scottc, C Wrena
a Department of
Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne, UK, b Department of
Paediatric Surgery, Royal Victoria Infirmary, Newcastle upon Tyne, c Regional Maternity Survey
Office, 25 Claremont Place, Newcastle upon Tyne
Correspondence to: Dr Leonard, Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK Christopher.Wren{at}tfh.nuth.northy.nhs.uk
Accepted 6 July 2001
OBJECTIVE
To examine
the prevalence of congenital heart disease in babies with oesophageal
atresia and its influence on outcome.
DESIGNRetrospective analysis.
SETTINGThe resident
population of one health region.
RESULTSA total of 153 babies with oesophageal atresia were identified from 509 975 live
births (0.30 per 1000); 26 (17%) had cardiac defects. Survival of
babies with normal hearts was 97%, 97%, and 95% at one week, one
month, and one year. Survival of babies with congenital heart disease
was 85%, 85%, and 67% at one week, one month, and one year, but only
one of ten deaths was the result of the congenital heart disease. The
remaining deaths were due to other congenital malformations,
respiratory disease, or chromosome abnormalities.
CONCLUSIONSThere is a
high prevalence of congenital heart disease in babies with oesophageal
atresia. Congenital heart disease is associated with a higher mortality
in oesophageal atresia but it is not the cause of it.
Keywords: heart disease; oesophageal atresia; congenital anomalies; mortality
© 2001 by Archives of Disease in Childhood
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