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Archives of Disease in Childhood - Fetal and Neonatal Edition 2002;86:F75-F77; doi:10.1136/fn.86.2.F75
Copyright © 2002 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood Fetal and Neonatal Edition 2002;86:F75-F77
© 2002 Archives of Disease in Childhood Fetal and Neonatal Edition

REVIEW

The clinical conundrum of neonatal seizures

M Levene

Academic Unit of Paediatrics, Obstetrics and Gynaecology, University of Leeds, D Floor, Clarendon Wing, Leeds LS2 9NS, UK

Correspondence to:
Correspondence to:
Professor Levene, Academic Unit of Paediatrics, Obstetrics and Gynaecology, University of Leeds, D Floor, Clarendon Wing, Leeds LS2 9NS, UK;
medmil{at}leeds.ac.uk

ABSTRACT

There is increasing evidence that neonatal seizures have an adverse effect on neurodevelopmental progression and may predispose to cognitive, behavioural, or epileptic complications later in life. However, given the uncertainty about the efficacy and toxicity of the commonly used anticonvulsants, when and how aggressively to treat such seizures is a difficult decision.

Keywords: brain; seizures; convulsions; anticonvulsants


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  • Glass, H. C., Wirrell, E. (2009). Controversies in Neonatal Seizure Management. J Child Neurol 24: 591-599 [Abstract]  
  • Murray, D M, Boylan, G B, Ali, I, Ryan, C A, Murphy, B P, Connolly, S (2008). Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures. Arch. Dis. Child. Fetal Neonatal Ed. 93: F187-F191 [Abstract] [Full Text]  
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