© 2002 Archives of Disease in Childhood Fetal and Neonatal Edition
SHORT REPORT
Reduced birth weight in boys with hypospadias: an index of androgen dysfunction?
1 Department of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, Box 116, Cambridge CB2 2QQ, UK
2 Unit of Paediatric and Perinatal Epidemiology, Division of Child Health, University of Bristol, 24 Tyndale Avenue, Bristol BS8 1TQ, UK
Correspondence to:
Correspondence to:
Professor Hughes, Department of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, Box 116, Cambridge CB2 2QQ, UK;
iah1000{at}cam.ac.uk
Anthropometric birth measurements analysed for 51 boys with hypospadias identified in a prospective cohort study showed significant reductions in mean values for birth weight, length, and head circumference compared with controls. The absence of the usual sex dimorphism for these variables suggests that the results represent a marker of fetal androgen dysfunction in this subgroup of infants.
Keywords: birth weight; boys; hypospadias
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