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Archives of Disease in Childhood Fetal and Neonatal Edition 2003;88:F56-F57
© 2003 Archives of Disease in Childhood Fetal and Neonatal Edition


SHORT REPORT

Iodine deficiency associated with parenteral nutrition in extreme preterm infants

M Ibrahim1, G Morreale de Escobar2, T J Visser3, S Durán2, H van Toor3, J Strachan4, F L R Williams5, R Hume1

1 Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
2 Departmento de Endocrinologia, Instituto de Investigaciones Biomedicas "Alberto Sols" Arturo Duperier 4, Spanish Research Council and Autonomous University of Madrid, Madrid 28029, Spain
3 Department of Internal Medicine III, Erasmus University, University Hospital Dijkzigt, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
4 Department of Biochemical Medicine, Ninewells Hospital and Medical School
5 Department of Epidemiology and Public Health, University of Dundee, Ninewells Hospital and Medical School

Correspondence to:
Correspondence to:
Professor Hume, Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland UK;
r.hume{at}dundee.ac.uk


ABSTRACT
Infants are in negative iodine balance on current standard regimens of total parenteral nutrition, with a mean iodine intake of 3 µg/kg/day (150 ml/kg/day). The recommended enteral intake of iodine for preterm infants is 30 µg/kg/day. Gastrointestinal absorption of iodine is high, suggesting that parenteral intakes should approach enteral recommendations.


Keywords: preterm; iodine; thyroid; parenteral nutrition




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