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Perinatal pathology in the context of a clinical trial: a review of the literature

¹ Medical Statistics Unit, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK
² Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK

Correspondence to:
Correspondence to:
C Snowdon
Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK; cms1000{at}cam.ac.uk

ABSTRACT
Perinatal postmortem rates are declining world wide. In the United Kingdom, perinatal pathology has recently been seriously undermined by controversy. There are important consequences for perinatal trials that include pathology studies. This review looks at the reasons for the decline in perinatal postmortem examinations and the effects on research.

Keywords: pathology; post mortem examinations; randomised controlled trials; attitudes; consent

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