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Archives of Disease in Childhood - Fetal and Neonatal Edition 2004;89:F200-F203; doi:10.1136/adc.2002.012740
Copyright © 2004 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood Fetal and Neonatal Edition 2004;89:F200
© 2004 Archives of Disease in Childhood Fetal and Neonatal Edition

REVIEW

Perinatal pathology in the context of a clinical trial: a review of the literature

C Snowdon1,2, D R Elbourne1 and J Garcia1

1 Medical Statistics Unit, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK
2 Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK

Correspondence to:
Correspondence to:
C Snowdon
Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK; cms1000{at}cam.ac.uk

ABSTRACT

Perinatal postmortem rates are declining world wide. In the United Kingdom, perinatal pathology has recently been seriously undermined by controversy. There are important consequences for perinatal trials that include pathology studies. This review looks at the reasons for the decline in perinatal postmortem examinations and the effects on research.

Keywords: pathology; post mortem examinations; randomised controlled trials; attitudes; consent


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This article has been cited by other articles:

  • (2004). Perinatal postmortems: professionals, parents, and clinical trials. J. Clin. Pathol. 57: 701-701 [Full Text]  
  • McDermott, M (2004). The continuing decline of autopsies in clinical trials: is there any way back?. Arch. Dis. Child. Fetal Neonatal Ed. 89: F198-F199 [Full Text]  
  • Snowdon, C, Elbourne, D R, Garcia, J (2004). Perinatal pathology in the context of a clinical trial: attitudes of neonatologists and pathologists. Arch. Dis. Child. Fetal Neonatal Ed. 89: F204-F207 [Abstract] [Full Text]  
  • Snowdon, C, Elbourne, D R, Garcia, J (2004). Perinatal pathology in the context of a clinical trial: attitudes of bereaved parents. Arch. Dis. Child. Fetal Neonatal Ed. 89: F208-F211 [Abstract] [Full Text]  

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