© 2005 Archives of Disease in Childhood Fetal and Neonatal Edition
REVIEW
Neonatal sepsis: an international perspective
1 International Perinatal Care Unit, Centre for International Child Health, Institute of Child Health, University College London, London WC1N 1EH, UK
2 Consultant Paediatric Infectious Diseases, St George’s Hospital Medical School, London SW17 0RE, UK
3 Paediatric Department, Kamuzu Central Hospital, Lilongwe, Malawi
Correspondence to:
Correspondence to:
Dr Vergnano
International Perinatal Care Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK; s.vergnano{at}ich.ucl.ac.uk
Neonatal infections currently cause about 1.6 million deaths annually in developing countries. Sepsis and meningitis are responsible for most of these deaths. Resistance to commonly used antibiotics is emerging and constitutes an important problem world wide. To reduce global neonatal mortality, strategies of proven efficacy, such as hand washing, barrier nursing, restriction of antibiotic use, and rationalisation of admission to neonatal units, need to be implemented. Different approaches require further research.
Abbreviations: CONS, coagulase negative staphylococci; EOS, early onset; GBS, group B streptococcus; LOS, late onset
Keywords: sepsis; developing countries; meningitis; group B streptococcus; nosocomial infections
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