|
|
||||||||||||||
|
|
|||||||||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ORIGINAL ARTICLE |
1 Kaiser Permanente Medical Care Program, Division of Research, Perinatal Research Unit, Oakland, CA, USA
2 Kaiser Permanente Medical Center, Department of Pediatrics, Walnut Creek, CA, USA
3 Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA, USA
4 Department of Neonatology, Beth Israel Deaconess Medical Center, Boston
5 Harvard Medical School, Department of Newborn Medicine, Brigham and Womens Hospital, Boston
Correspondence to:
Correspondence to:
Dr Escobar
Kaiser Permanente Medical Care Program, Division of Research, Perinatal Research Unit, 2000 Broadway, 2nd floor, Oakland, CA 94612, USA; gabriel.escobar{at}kp.org
Background: Newborns of 3034 weeks gestation comprise 3.9% of all live births in the United States and 32% of all premature infants. They have been studied much less than very low birthweight infants.
Objective: To measure in-hospital outcomes and readmission within three months of discharge of moderately premature infants.
Design: Prospective cohort study including retrospective chart review and telephone interviews after discharge.
Setting: Ten birth hospitals in California and Massachusetts.
Patients: Surviving moderately premature infants born between October 2001 and February 2003.
Main outcome measures: (a) Occurrence of assisted ventilation during the hospital stay after birth; (b) adverse in-hospital outcomesfor example, necrotising enterocolitis; (c) readmission within three months of discharge.
Results: With the use of prospective cluster sampling, 850 eligible infants and their families were identified, randomly selected, and enrolled. A total of 677 families completed a telephone interview three months after hospital discharge. During the birth stay, these babies experienced substantial morbidity: 45.7% experienced assisted ventilation, and 3.2% still required supplemental oxygen at 36 weeks. Readmission within three months occurred in 11.2% of the cohort and was higher among male infants and those with chronic lung disease.
Conclusions: Moderately premature infants experience significant morbidity, as evidenced by high rates of assisted ventilation, use of oxygen at 36 weeks, and readmission. Such morbidity deserves more research.
Abbreviations: NICU, neonatal intensive care unit; PMA, postmenstrual age
Keywords: assisted ventilation; outcomes; prematurity; morbidity; intensive care
This article has been cited by other articles:
![]() |
M. C. McCormick, G. J. Escobar, Z. Zheng, and D. K. Richardson Factors Influencing Parental Satisfaction With Neonatal Intensive Care Among the Families of Moderately Premature Infants Pediatrics, June 1, 2008; 121(6): 1111 - 1118. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. K. Shapiro-Mendoza, K. M. Tomashek, M. Kotelchuck, W. Barfield, A. Nannini, J. Weiss, and E. Declercq Effect of Late-Preterm Birth and Maternal Medical Conditions on Newborn Morbidity Risk Pediatrics, February 1, 2008; 121(2): e223 - e232. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Lindstrom, B. Winbladh, B. Haglund, and A. Hjern Preterm Infants as Young Adults: A Swedish National Cohort Study Pediatrics, July 1, 2007; 120(1): 70 - 77. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Profit, M. C. McCormick, G. J. Escobar, D. K. Richardson, Z. Zheng, K. Coleman-Phox, R. Roberts, and J. A.F. Zupancic Neonatal Intensive Care Unit Census Influences Discharge of Moderately Preterm Infants Pediatrics, February 1, 2007; 119(2): 314 - 319. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS | REGISTER |
| ARCH DIS CHILD | FETAL NEONATAL ED | ED PRACTICE |