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Published Online First: 24 January 2007. doi:10.1136/adc.2006.096479
Archives of Disease in Childhood - Fetal and Neonatal Edition 2007;92:F251-F254
Copyright © 2007 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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ORIGINAL ARTICLE

Severe retinopathy of prematurity in infants <30 weeks’ gestation in New South Wales and the Australian Capital Territory from 1992 to 2002

D A Todd1, A Wright2, J Smith2 the NICUS Group*

1 Neonatal Intensive Care Unit, The Canberra Hospital, Woden, Australian Capital Territory, Australia
2 Neonatal Intensive Care Unit, Westmead Hospital, Westmead, New South Wales Australia

Correspondence to:
Correspondence to:
Dr David A Todd
Neonatal Intensive Care Unit, The Canberra Hospital, PO Box 11, Woden, ACT Australia, 2606; David.Todd{at}act.gov.au

Background: Retinopathy of prematurity (ROP) significantly increased in New South Wales (NSW) from 1986 to 1994, but more recent data suggest that there has now been a decrease.

Objective: To study the incidence and treatment of severe ROP (stage >=3) in NSW and the Australian Capital Territory (ACT) from 1992 to 2002.

Methods: Data collected prospectively from the Neonatal Intensive Care Units’ (NICUS) Data Collection over an 11-year period in infants <30 weeks’ gestation were divided into four epochs and analysed retrospectively. The incidence and treatment of severe ROP were compared for gestational ages <=24 weeks’, 25–26 weeks’ and 27–29 weeks’ gestation over the four epochs.

Results: In infants <=24 weeks’ gestation the incidence of severe ROP and those treated increased significantly (stage >=3: from 17 (41.5%) to 41 (53.9%), p = 0.052; treated: from 8 (19.5%) to 25 (32.9%), p<0.05 (first and fourth epoch)). In infants 25–26weeks’ gestation the incidence of severe ROP decreased significantly whereas there was a non-significant increase in those treated (stage >=3: from 55 (26.2%) to 46 (19.3%), p<0.05; treated: from 19 (9.0%) to 32 (13.4%)). In infants 27–29 weeks’ gestation, there was no significant change in the incidence of severe ROP or those treated (stage >=3: from 30 (4.1%) to 17 (2.4%); treated: from 14 (1.9%) to 8 (1.1%)).

Conclusion: In infants <=24 weeks’ gestation there has been a significant increase in severe ROP, and in infants <27 weeks’ gestation the numbers treated for severe ROP increased.


Abbreviations: ACT, Australian Capital Territory; NSW, New South Wales; ROP, retinopathy of prematurity

Keywords: retinopathy of prematurity; preterm infants; cryo-therapy and laser therapy


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Arch. Dis. Child. Fetal Neonatal Ed. 2007 92: F235. [Extract] [Full Text] [PDF]



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