SHORT REPORT

Morphine versus remifentanil for intubating preterm neonates

Yerkes Pereira e Silva¹, Renato Santiago Gomez², Juliana de Oliveira Marcatto¹, Thadeu Alves Maximo³, Rosilu Ferreira Barbosa¹ and Ana Cristina Simões e Silva³

¹ Departments of Anesthesiology and Neonatology of the Lifecenter Hospital, Belo Horizonte, Minas Gerais, Brazil
² Department of Surgery of the Medical Faculty from Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
³ Department of Pediatrics of the Medical Faculty from Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Correspondence to:
Correspondence to:
Dr Yerkes Pereira e Silva
Rua Montevideu, 402—Apartment 402, Sion, Belo Horizonte, MG, Brazil; yerkesps{at}uol.com.br

A double-blind, randomised controlled study was conducted to evaluate the intubation conditions in 20 preterm neonates following the use of either morphine or remifentanil as premedication. The findings suggest that the overall intubation conditions were significantly better (p = 0.0034) in the remifentanil group than in the morphine group. No severe complications were observed in either group.

Abbreviations: NICU, neonatal intensive care unit; NIPS, neonatal infant pain scale; RDS, respiratory distress syndrome

Keywords: intubation; preterm neonate; remifentanil; morphine; pain

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• Greenwood, C. S., Colby, C. E. (2009). Pharmacology Review: Premedication for Endotracheal Intubation of the Neonate: What is the Evidence?. NeoReviews 10: e31-e35 [Abstract] [Full Text]  
• VanLooy, J., Schumacher, R. E, Bhatt-Mehta, V. (2008). Efficacy of a Premedication Algorithm for Nonemergent Intubation in a Neonatal Intensive Care Unit. The Annals of Pharmacotherapy 42: 947-955 [Abstract] [Full Text]