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Published Online First: 11 January 2008. doi:10.1136/adc.2007.125377
Archives of Disease in Childhood - Fetal and Neonatal Edition 2008;93:F240-F241
Copyright © 2008 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

CASE REPORT

Transient neonatal diabetes mellitus in extremely preterm infant

S Nishimaki1,2,3,4, T Yukawa1,2,3,4, Y Makita1,2,3,4, H Honda1,2,3,4, N Kikuchi1,2,3,4, S Minamisawa1,2,3,4 and S Yokota1,2,3,4

1 Departments of Paediatrics, Yokohama City University, Japan
2 Department of Paediatrics, Asahikawa Medical College, Japan
3 Department of Paediatrics, Yokosuka kyosai Hospital, Japan
4 Cardiovascular Research Institute, Yokohama City University, Japan

Correspondence to:
Dr S Nishimaki, Department of Paediatrics, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan; shigenis{at}med.yokohama-cu.ac.jp

A report of transient neonatal diabetes mellitus in an extremely preterm infant (gestational age 27 weeks, birth weight 718 g). The patient had intrauterine growth retardation and developed hyperglycaemia on the first day of life. Insulin administration was discontinued on the 89th day of life, which was 1 day before the original due date. This case suggests that (a) insufficient insulin secretion started at least from the second trimester of the pregnancy; (b) the duration needed for recovery of insulin secretion was not dependent on the maturity.


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Management of neonatal diabetes mellitus
Cheri Mathews John
Fetal Neonatal Ed. Online, 12 May 2008 [Full text]

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