Arch Dis Child Fetal Neonatal Ed 2001;84:F140
( March )
Letters to the editor
Dexamethasone treatment and
cerebral palsy
| The first 150 words of the full text of this article appear below. |
EDITOR
Referring to the paper entitled Early
postnatal dexamethasone treatment and increased incidence of cerebral
palsy by Shinwell et al1, both
its title and the first paragraph of the Discussion imply that the use
of postnatal dexamethasone may lead to cerebral palsy. However, it is
the misuse of the term "incidence" that gives rise to this
interpretation. The authors did not, neither could they, provide
incidence data. What they presented was cerebral palsy prevalence data.
If it is accepted that prevalence and not incidence data are provided,
then a very different interpretation of the findings can be made.
Supposing the cerebral impairment of cerebral palsy occurred prepartum,
then the use of dexamethasone may have allowed these children to
survive, whereas, had they received the placebo, they would have died
before a diagnosis of cerebral palsy could be made. This would account
for the higher prevalence of cerebral palsy . . . [Full text of this article]