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Standardised feeding regimens: hope for reducing the risk of necrotising enterocolitis

Correspondence to:
Correspondence to:
Dr Premji
University of Calgary, Faculty of Nursing, 2500 University Dr NW, Calgary, AB, Canada, T2N 1N4; premjis@ucalgary.ca

Abbreviations: NEC, necrotising enterocolitis; SFR, standardised feeding regimen

Keywords: necrotising enterocolitis; feeding intolerance; guidelines; low birth weight

The first 150 words of the full text of this article appear below.

Necrotising enterocolitis (NEC), an acquired gastrointestinal disease in neonatal intensive care unit survivors, affects one to three infants per 1000 live births and is associated with significant mortality and morbidity.^2,3 Although it has not been proven, many believe that, in premature infants, a precursor to NEC is feeding intolerance, specifically, prefeed gastric residuals or bile stained aspirates.^4–6 These associated intestinal signs of NEC may also reflect a delay in maturation of the neonate’s motor activity such that they lack complete interdigestive cycles during fasting. As no biological markers exist to diagnose NEC, clinical wisdom guides decision making related to its diagnoses and management. Furthermore, there is a paucity of research identifying feeding practices, except for breast milk feeds, that offer the greatest potential benefit against developing NEC. Moreover, hormonal, anatomical, and functional limitations of low birthweight infants, the additive effects of critical illness, and intrauterine environmental factors—for example, . . . [Full text of this article]

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				J W L Puntis Nutritional support in the premature newborn. Postgrad. Med. J., March 1, 2006; 82(965): 192 - 198. [Abstract] [Full Text] [PDF]