HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this link to a friend Similar articles in ADC Online Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Marlow, N Articles by Budge, H Search for Related Content PubMed PubMed Citation Articles by Marlow, N Articles by Budge, H

Prevalence, causes, and outcome at 2 years of age of newborn encephalopathy

Academic Division of Child Health, School of Human Development, University of Nottingham, Nottingham, UK

Correspondence to:
Correspondence to:
Professor Marlow
Academic Division of Child Health, Level E East Block, Queen’s Medical Centre, Nottingham NG7 2UH, UK; neil.marlow@nottingham.ac.uk

Keywords: encephalopathy; outcome; prevalence; population based study

The first 150 words of the full text of this article appear below.

Regional population based studies of infants who suffer from intrapartum hypoxia are rare, and Pierrat and colleagues are to be congratulated on such a study. As always it is easy to criticise such studies because case definition is so difficult, and, without accurate imaging and detailed case evaluation, it is difficult to be sure that a neonatal encephalopathy is due to hypoxia. The definition of perinatal hypoxia-ischaemia that they have used might be viewed as inclusive and is at variance with the template for intrapartum causation for cerebral palsy, which requires evidence of an intrapartum event.¹ Without detailed evaluation of each case, it is difficult to be certain of the timing of the cause.

In the literature, most outcome evaluations of neonatal populations have studied very preterm infants, and there have been only a few population studies of neonatal encephalopathy. The birth prevalence of encephalopathy reported in this paper . . . [Full text of this article]