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Archives of Disease in Childhood - Fetal and Neonatal Edition 2008;93:F304; doi:10.1136/adc.2007.136903
Copyright © 2008 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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IMAGES IN NEONATAL MEDICINE

Rapid diagnosis of cerebral sinovenous thrombosis complicating group B streptococcus meningitis by multidetector CT venography

H M Cheung1, W C W Chu2, H S Lam1, P C Ng1

1 Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
2 Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong

Correspondence to:
Professor P C Ng, Department of Paediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Shatin, NT, Hong Kong; pakcheungng@cuhk.edu.hk

The first 150 words of the full text of this article appear below.

A full-term infant delivered vaginally developed fever and refractory seizures at 34 h of age, ultimately requiring thiopentone anaesthesia. Cerebrospinal fluid and peripheral blood cultures isolated Streptococcus agalactiae. Urgent plain cranial CT revealed a hypo-attenuated area in the left occipital region (fig 1). A multidetector computed tomographic (MDCT) venogram showed a large filling defect almost totally obliterating the left cerebral transverse sinus (fig 2) and confirmed the diagnosis of sinovenous thrombosis with venous infarction of the drainage territory.


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Figure 1 CT brain scan showing a hypo-attenuated area in the left occipital region (arrows). The appearance is highly suggestive of venous infarction.

 

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Figure 2 Multidetector computed tomographic venogram showing filling defect (arrow) representing a giant thrombus within the left transverse sinus.

 
In the past, early diagnosis of cerebral sinovenous thrombosis was hampered by the need for invasive angiography and insensitive neuroimaging techniques.1 2 MDCT venography, with the capability of submillimetre slices, . . . [Full text of this article]







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