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Arch Dis Child Fetal Neonatal Ed 77:F16-F22 doi:10.1136/fn.77.1.F16
  • Original article

Endothelial nitric oxide synthase in hypoxic newborn porcine pulmonary vessels

Table 2

Mean (SD) percentage of arteries containing different amounts of eNOS within endothelial cells

Artery level 0-2.5H+1R 0-2.5H+3R 0-2.5H+6R 3-6H+1R 3-6H+3R 3-6H+6R 14-17H+1R 14-17H+3R 14-17H+6R
Bronchiolus
 0 15  (1.4) 7  (10.4) 15.5  (6.4) 14  (15.6) 16  (7.2) 19.8  (14.9) 8.5  (2.1) 15.7  (5.1) 13  (7.8)
 1-50 51 (9.9) 24.3 (21.8) 52 (16.04) 42 (21.2) 42 (4.4) 44.2 (21.5) 37 (5.6) 43.3 (9.9) 45.5 (5.1)
 51-100 34 (8.4) 68.7 (30.5) 43.5 (36.1) 43.5 (36.1) 42 (10.5) 36 (35.2) 54.5 (7.8) 41 (7.5) 41.5 (5)
Terminal bronchiolus
 0 22 (12.7) 8.3 (9.6) 22.5 (8.3) 16 (15.6) 28 (30.3) 23.7 (20.4) 14.5 (7.8) 29.7 (19.1) 15 (13.1)
 1-50 60 (14.1) 45.3 (23.0) 60.2 (11.6) 44 (12.7) 45.7 (8)  47.8 (11.6) 29 (15.6) 54.3 (20.8) 60.25 (14.5)
 51-100 18 (1.4) 45.7 (28.0) 17.2 (13.6) 40 (28.2) 26 (22.7) 24.5 (29.4) 56.5 (27.3) 17.7 (18.1) 24.75 (22.4)
Respiratory bronchiolus
 0 28.5 (10.6) 6.7 (5.9) 39.7 (10.3) 22 (19.8) 27.7 (18.6) 27 (18.2) 14.5 (7.8) 21.3 (7.2) 24.25 (12.6)
 1-50 70 (8.4) 54.3 (21.8) 47.2 (11.4) 53 (15.5) 51.3 (14.8) 47.5 (14.4) 58.5 (7.8) 70.7 (6.7) 50.75 (11.5)
 51-100 1.5 (2.1) 39 (2.7) 13 (9.3 25 (35.3) 25 (35.3) 24.7 (32.9) 27 (0) 8 (7) 24.5 (14.1)
Alveolar duct
 0 49 (1.4) 9 (5.2) 56.2 (31.5) 41.5 (12.02) 38.5 (7.6) 36.2 (17.1) 35 (7.1) 49.7 (18.0) 39 (26)
 1-50 41 (5.3) 46 (14.4) 37.2 (27.9) 31 (19.8) 50 (3) 47.8 (15.1) 44.5 (10.6) 43.7 (10.1 40 (11.7)
 51-100 9.7 (3.9) 45 (16.5) 6.5 (14.5) 22.5 (31.8) 10.3 (5.8) 16 (19.1) 20.5 (17.7) 6.7 (8.3) 21 (16.3)
Alveoli
 0 100 73.7 (25.1) 98 (4) 100 100 100 77.5 (31.8) 90.3 (16.7) 92.5 (5)
 1-50 0 21.3 (25.7)  2 (4)  0 0 0 22.5 (31.8) 9.7 (16.7) 7.5 (5)
 51-100 0 4.7 (8.1)  0  0 0 0 0 0 0
  • H = Days of hypoxia; R = days of recovery.

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