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Arch Dis Child Fetal Neonatal Ed 77:F32-F35 doi:10.1136/fn.77.1.F32
  • Original article

Pulmonary function changes after nebulised and intravenous frusemide in ventilated premature infants

Table 3

Effect of frusemide on 6 hour urine output and urinary electrolyte excretion in premature infants (values are mean (SE))

Urine measurement Route of frusemide administration
Intravenous Nebulised
Before After P value Before After P value
Output (ml/kg/hour) 3.3 (0.4) 5.9 (0.8) 0.006 3.0 (0.5) 2.9 (0.4) 0.84
Sodium (mEq/kg/hour) 0.8 (0.1) 2.7 (0.6) 0.004 0.8 (0.1) 0.6 (0.1) 0.03
Potassium (mEq/kg/hour) 0.3 (0.1) 0.5 (0.1) 0.01 0.4 (0.1) 0.4 (0.1) 0.91
Chloride (mEq/kg/hour) 0.9 (0.1) 2.5 (0.5) 0.005 0.9 (0.2) 0.7 (0.1) 0.03

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