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Arch Dis Child Fetal Neonatal Ed 78:F125-F128 doi:10.1136/fn.78.2.F125
  • Original article

Complement and contact activation in term neonates after fetal acidosis

Table 2

Comparison of concentration and activities of complement factors and Hageman factor between acidosis and control groups (median with quartiles)

Acidosios group (n=15) Control group (n=15) p Value
Complement function test (%)  46  (24/52)  73  (60/90) 0.001
C1q concentration (mg/dl) 4.3   (3.5/5.7) 9.1   (8.2/9.7) < 0.0001
Factor B (mg/dl) 5.2   (4.3/7.9) 7.7   (6.9/9.3) 0.02
C3a (μg/l) 260  (180/705) 185  (100/260) 0.04
C5a (μg/l) 5.0   (0.6/10.5) 0.6   (0.55/1.2) 0.005
Factor XIIa (μg/l) 3.2   (1.3/6.4) 1.3   (0.8/1.9) 0.02
C1 inhibitor concentration (g/l) 0.12 (0.08/0.15) 0.12 (0.10/0.16) NS
C1 inhibitor activity (%)  65  (55/103)  75  (55/110) NS

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