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Arch Dis Child Fetal Neonatal Ed 78:F151-F153 doi:10.1136/fn.78.2.F151
  • Original article

Long term gastric pH monitoring for determining optimal dose of ranitidine for critically ill preterm and term neonates

Table 2

Mean time (h) gastric pH stays over 4 in preterm and term infants after receiving three different doses of ranitidine

Gestational age (weeks) Different doses of ranitidine treatment (mg/kg body weight)
0.5 1.0 1.5
mean (h) SD N mean (h) SD N mean (h) SD N
28–36 10.17 1.3 3 12.75 2.2 4 20.75 1.1 2
37–42 4.75 1.1 2 6.50 1.4 2 7.67 0.8 3
  • Two way analysis of variance: weeks: p<0.001, dose: p<0.001, interaction p=0.005.

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