rss
Arch Dis Child Fetal Neonatal Ed 78:F199-F203 doi:10.1136/fn.78.3.F199
  • Original article

Prediction of individual response to postnatal dexamethasone in ventilator dependent preterm infants

Table 3

Characteristics of infants grouped according to extubation within one week of dexamethasone (values are expressed as median with range or number and percentage)

Extubation 6 days
or less
Extubation 7 days
or more
p Value
(n=36) (n=33)
Gestation (weeks)  26 (24–31)  25 (24–29)  0.0017
Birthweight (g) 925 (539–1845) 810 (560–1260)  0.03
Antenatal steroids (complete course)  66%  61%  0.78
Respiratory distress syndrome  81%  80%  0.44
Pneumothorax requiring intercostal drain   3%  21%  0.01
Symptomatic PDA  51%  70%  0.123
PIE on pre-dexamethasone x ray picture  13%  72% <0.0001
Northway stage
 1  47%  13%
 2  23%  56%  0.005
 3  30%  31%
VI before dexamethasone  46.8 (5.9–88.5)  60.9 (19.8–104.0)  0.02
Age at dexamethasone (days)  11.5 (6–31)  10 (3–31)  0.06
Length of course (days)  19 (3–43)  30 (3–57)  0.0903
VI at 36–48 hours (percentage of pre-dexamethasone VI)   33 (0–74)  58 (18–173) <0.0001
Days to extubation   3 (1–6)  14.5 (7–46) <0.0001
Corrected gestational age at extubation, weeks  29.1 (25.9–33.0)  29.0 (27.3–31.6)  0.98

This Article

Latest from Education & Practice

Latest from Education & Practice

Register for free content

Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of ADC Fetal & Neonatal.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • Paediatrics and Paediatric Surgery Jobs

    Paediatrics and Paediatric Surgery Jobs