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Arch Dis Child Fetal Neonatal Ed 79:F180-F184 doi:10.1136/fn.79.3.F180
  • Original article

Circulatory changes induced by isovolumic increase in red cell mass in fetal lambs

Table 2

Changes observed in ventricular outputs and pulsatility indices with progressive increase in haematocrit

ID Steps RVOw (ml) ΔRVOw (ml) LVOw (ml) ΔLVOw (ml) daPI ΔdaPI cPI ΔcPI uPI ΔuPI
LAO 1B 153 102 1.11 2.0 0.60
NOR 1B 235 135 1.45 1.74 0.33
QUE 1B 257 234 2.03 1.91 0.75
TAN 1B 112 67 1.26 1.29 0.51
URU 1B 193 115 0.81 1.52 0.40
LAO 2M 161 8 103 1 1.51 0.40 2.52 0.52 0.44 −0.16
NOR 2M 165 −71 101 −34 1.03 −0.42 1.81 0.08
QUE 2M 242 −14 154 −80 0.93 −1.10 1.89 −0.02 0.74 0.00
TAN 2M 108 −5 55 −13 1.39 0.13 1.71 0.42 0.62 0.10
URU 2M 109 −85 121 6 1.02 0.21 1.60 0.08 0.84 0.44
LAO 3H 114 −39 73 −29 1.54 0.43 3.70 1.70 0.39 −0.21
NOR 3H 133 −102 89 −46 0.87 −0.58 2.18 0.45 0.35 0.02
QUE 3H 225 −31 134 −100 0.98 −1.05 2.87 0.96 0.73 −0.02
TAN 3H 74 −39 34 −33 1.21 −0.05 3.63 2.34 0.64 0.13
URU 3H 131 −63 104 −11 0.98 0.17 1.65 0.13 0.78 0.38
AVG (B) 190.14 130.7 1.33 1.69 0.52
STD 59 62.6 0.46 0.29 0.16
AVG (M) 156.8 −33.4 106.7 −24 1.18 −0.15 1.91 0.22 0.66 0.10
STD 55.1 41.6 36 34.7 0.26 0.61 0.36 0.24 0.17 0.26
AVG (H) 135.3 −54.9 86.8 −43.9 1.12 −0.22 2.81 1.11 0.58 0.06
STD 55.7 29.1 36.9 33.7 0.27 0.6 0.90 0.2 0.22
Friedman ANOVA p 0.05 0.05 >0.05 0.015 >0.05

  • B, M and H: basal, moderate, and high haematocrit, respectively; RVOw: right ventricular output/kg; LVOw: left ventricular output/kg; daPI, cPI, and uPI: pulsatility index in descending aorta, carotid, and umbilical arteries, respectively.

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