Predictive value of plasma and cerebrospinal fluid tumour necrosis factor-α and interleukin-1β concentrations on outcome of full term infants with hypoxic–ischaemic encephalopathy

Table 3

Cerebrospinal fluid TNF-α and IL-1β concentrations of group 1 and 2

	Group 1 (n=11)	Group 2a (n=14)^3-160	Group 2b (n=5)^3-151	p^3-164
TNF-α (CSF)^3-150
Mean (SEM)	62.2 (20.14)	94.71 (29.84)	178 (54.89)	0.01
Median	37	63.5	123	(0.1)^3-152
Range	15.6–248	27–468	75–356
IL-1β (CSF)^3-150
Mean (SEM)	0.90 (0.29)	3.5 (0.67)	5.68 (0.75)	0.002
Median	0.48	3.7	5.4	(0.01)^3-152
Range	0.125–3.3	0.125–7.4	3.6–8.0

↵3-150 All cytokine concentrations are pg/ml.
↵3-160 Group 2a, survivors.
↵3-151 Group 2b, non-survivors.
↵3-164 Significance between the 3 groups (p<0.05 as significant).
↵3-152 Significance between group 1 and group 2a (p<0.05 as significant).

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Predictive value of plasma and cerebrospinal fluid tumour necrosis factor-α and interleukin-1β concentrations on outcome of full term infants with hypoxic–ischaemic encephalopathy

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