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Arch Dis Child Fetal Neonatal Ed 79:F218-F220 doi:10.1136/fn.79.3.F218
  • Original article

Effect of vitamin K1 on glucose-6-phosphate dehydrogenase deficient neonatal erythrocytes in vitro

Table 1

Mean (SD) GSH and metHb values before and after incubation with vitamin K1

Baseline Incubation at 44 μM vitamin K1 % change1-150
from baseline
Incubation at 444 μM vitamin K1 % change1-150
from baseline
GSH (μmol/g Hb)
 G-6-PD deficient (n=7) 1.97 (0.31) 1.89 (0.44)  −4.3 (13.1) 1.69 (0.41) −14.5 (9.3)
 G-6-PD normal (n=10) 2.27 (0.31) 2.09 (0.56)  −7.2 (23.2) 2.12 (0.38)  −6.0 (14.1)
 Significance of % change p=0.77 p=0.18
MetHb (% of total Hb)
 G-6-PD deficient (n=7) 2.01 (0.53) 1.93 (0.37)  −0.6 (17.4) 2.06 (0.43)   5.7 (14.2)
 G-6-PD normal (n=10) 1.56 (0.74) 1.70 (0.78) 12.7 (21.9) 1.78 (0.71) 20.6 (26.8)
 Significance of % change p=0.2 p=0.2
  • 1-150 As the mean percentage change was calculated by first calculating the percentage change of each individual specimens, and then the mean percentage change of these individual percentages, values for percentage change in the table may appear unrelated to the mean measured values.

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