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Arch Dis Child Fetal Neonatal Ed 1999;80:F72-F73 doi:10.1136/fn.80.1.F72
  • Original article

Outcome of mother to infant acquired GBV-C/HGV infection

  1. G Zuina,
  2. B Saccania,
  3. S Di Giacomoa,
  4. E Tanzib,
  5. A R Zanettib,
  6. N Principia
  1. aFourth Paediatric Department, Università di Milano, Istituto di Scienze Biomediche Sacco, via GB Grassi 74, 20157 Milano, Italy, bInstitute of Virology University of Milan
  1. Dr Giovanna Zuin.
  • Accepted 3 April 1998

Abstract

Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV-C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV-C/HGV and hepatitis C virus and HIV coinfection.

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