Effect of caffeine on neonatal splanchnic blood flow
- aDepartment of Neonatology, Jessop Hospital for Women, Leavygreave Road, Sheffield S3 7RE, bDepartment of Biomedical Science, University of Sheffield, cDepartment of Medical Physics, Leicester Royal Infirmary
- Dr Robert Coombs.
- Accepted 13 August 1998
Abstract
Doppler ultrasound was used to study the effect of the first intravenous dose of caffeine on splanchnic haemodynamics in preterm neonates. Peak systolic velocity in the superior mesenteric artery and coeliac axis was significantly reduced for 6 hours after caffeine infusion.
The effect of this reduction in blood flow to the neonatal gut is not known.









