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Arch Dis Child Fetal Neonatal Ed 80:F161-F166 doi:10.1136/fn.80.3.F161
  • Original article

Randomised controlled trial of vitamin D supplementation on bone density and biochemical indices in preterm infants

Table 4

Bone mineral content (BMC) (mg) and bone mineral density (BMD) (mg/cm2) at 3 and 6 months corrected age measured by dual energy x-ray absorptiometry at forearm shaft and distal forearm in preterm infants receiving different vitamin D doses

Group A 200 IU/kg of body weight/day up to 400 IU/day (n=21) Group B 960 IU/day (n=18)
Mean (SD) Mean (SD) Mean difference
(95% CI)
Forearm shaft: BMC at 3 months 255 (49) 258 (39) −3 (−32 to 27)
6 months 326 (67) 328 (56) −2 (−42 to 39)
BMD at 3 months 135 (16) 139 (9) −4 (−12 to 5)
6 months 150 (17) 152 (18) −2 (−14 to 9)
Distal forearm: BMC at 3 months 201 (37) 208 (33) −7 (−29 to 16)
6 months 274 (50) 272 (46) −1 (−29 to 33)
BMD at 3 months 109 (14) 113 (9) −4 (−12 to 4)
6 months 120 (13) 124 (11) −4 (−11 to 4)

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