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Arch Dis Child Fetal Neonatal Ed 81:F141-F143 doi:10.1136/fn.81.2.F141
  • Original article

Effect of fortification on the osmolality of human milk

Table 3

Difference between osmolality values (mean and 95 % confidence interval) of human milk after supplementation with different HMF at various concentrations observed at T2 (24 hours after reconstitution), T1 ( 10 minutes after), and T0 (theoretical osmolality)

N = T1-T0 T2-T1 T1-T0 vs T2- T1
HMF1 6 0.33; (−4.1 to 4.8); p<0.86 7.2; (3.7 to 10.6), p<0.005 P = 0.02
HMF2(2.5%) 10 13.2; (23 to 70) , p<0.001 21.5; (13.6 to 29.3), p< 0.001 P = 0.01
HMF2(5%) 7 23.4; (17.5 to 29.3), p<0.001 42; (29.7 to 54.3), p<0.001 P = 0.003
HMF3(2.5%) 4 17.5; (−1.3to 36.3), p = 0.06 28.3; (21.7 to 34.8), p<0.001 P = 0.25 NS
HMF3(5%) 6 31.5; (22.9 to 40.1), p<0.001 63.8; (52.6 to 75.0), p<0.001 P = 0.002
HMF4(4%) 7 24; (21.6 to 26.4), p<0.001 6.9; (4.8 to 9), p<0.001 P<0.0001
HMF5(4%) 7 26.7; (23.2 to 30.2), p<0.001 18.1; (14.7 to 21.5), p<0.001 P<0.001
  • Osmolality values are expressed in mosmol/kg H2O.

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