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Arch Dis Child Fetal Neonatal Ed 81:F221-F227 doi:10.1136/fn.81.3.F221
  • Original article

Pharmacokinetics and dose requirements of vancomycin in neonates

Table 5

Vancomycin dose guidelines

Serum creatinine concentration (μmol/l) Dose Dose interval
20–29 20 mg/kg 8 hours
30–39 20 mg/kg 12 hours
40–49 15 mg/kg 12 hours
50–59 12 mg/kg 12 hours
60–79 15 mg/kg 18 hours
80–100 15 mg/kg 24 hours
>100 15 mg/kg check trough at 24 hours   and dose according to measurements

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