rss
Arch Dis Child Fetal Neonatal Ed 2000;82:F14-F18 doi:10.1136/fn.82.1.F14
  • Original article

Randomised controlled trial of patient triggered and conventional fast rate ventilation in neonatal respiratory distress syndrome

  1. M W Beresford,
  2. N J Shaw,
  3. D Manning
  1. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS
  1. Dr N J Shaw
  • Accepted 1 August 1999

Abstract

AIM To compare patient triggered, with conventional fast rate, ventilation in a randomised controlled trial using the incidence of chronic lung disease as the primary outcome measure.

METHODS Three hundred and eighty six preterm infants with birthweights from 1000 to 2000 g, and requiring ventilation for respiratory distress syndrome within 24 hours of birth, were randomised to receive either conventional or trigger ventilation with the SLE 2000 ventilator.

RESULTS There were no significant differences in the incidence of chronic lung disease (28 day and 36 week definitions), death, pneumothorax, intraventricular haemorrhage, number of ventilator days, or length of oxygen dependency between groups.

CONCLUSIONS Patient triggered ventilation in preterm infants with respiratory distress syndrome is feasible. No significant differences, when compared with conventional fast rate ventilation in important medium and longer term outcome measures, were evident.

Footnotes

    This Article

    1. Abstract
    2. Full text
    3. PDF

    Responses

    1. Submit a response
    2. No responses published

    Register for free content

    The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

    Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.