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Arch Dis Child Fetal Neonatal Ed 84:F172-F176 doi:10.1136/fn.84.3.F172
  • Original article

A trial of recombinant human granulocyte colony stimulating factor for the treatment of very low birthweight infants with presumed sepsis and neutropenia

Table 2

Time to absolute neutrophil count (ANC) recovery, duration of antibiotic use, mechanical ventilation, and intensive care, and mortality

rhG-CSF (n=13) Placebo (n=15) p Value
Time to ANC recovery to >5 × 109/l (days) 2 (1–3) 5 (4–7) <0.001
Duration of antibiotics (days) 8 (6–16) 16 (13–35) 0.14
Duration of mechanical ventilation (days) 5 (3–13) 12 (6–34) 0.23
Duration of intensive care (days) 8 (3–17) 12 (8–34)
Deaths during 42 day study period 1 4 0.33
Total deaths at 6 and 12 months postmenstrual age 1 7 0.038
  • Where applicable, results are presented as median (interquartile range).

  • rhG-CSF, recombinant human granulocyte colony stimulating factor.

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