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Arch Dis Child Fetal Neonatal Ed 86:F16-F21 doi:10.1136/fn.86.1.F16
  • Original article

Joint association of Apgar scores and early neonatal symptoms with minor disabilities at school age

Table 5

Odds ratios (95% confidence interval) of pathological behavioural and academic scores among 727 infants at 8–13 years of age related to Apgar scores five minutes after delivery and symptoms that may indicate neonatal encephalopathy* (SNE)

Apgar 0–3 Apgar 4–6 Apgar 7–10
+ SNE (total=77) − SNE (total=78) + SNE (total=122) − SNE (total=152) + SNE (total=40) − SNE (total=258)
*Symptoms that may indicate neonatal encephalopathy were defined as seizures, feeding difficulties, and/or ventilator treatment in the first week of life. Their distribution related to Apgar scores are specified in table 1; †p=0.42; ‡p=0.40; §p=0.61; ¶p=0.45; **p=0.03; ††p=0.04; ‡‡p=0.009; §§p=0.01; ¶¶p=0.06; ***none in the cell; †††p=0.003; ‡‡‡p=0.004; §§§defined as pathological score of at least one of the other items. p<0.00005.
Attention† 1.5 (0.5 to 5.1) 1.1 (0.3 to 4.2) 2.7 (1.1 to 6.8) 1.5 (0.6 to 4.1) 1.5 (0.3 to 7.0) 1.0 (ref)
Habituation‡ 3.6 (1.0 to 12.6) 2.7 (0.7 to 10.4) 2.2 (0.6 to 7.6) 1.4 (0.4 to 5.2) 2.7 (0.5 to 14.2) 1.0 (ref)
Impulsivity§ 1.4 (0.5 to 4.2) 2.0 (0.8 to 5.3) 1.2 (0.5 to 3.2) 0.7 (0.2 to 2.0) 1.1 (0.2 to 5.0) 1.0 (ref)
Activity¶ 2.1 (0.5 to 8.9) 3.5 (1.0 to 12.3) 2.6 (0.8 to 8.8) 1.7 (0.5 to 6.1) 2.7 (0.5 to 14.7) 1.0 (ref)
Tractability** 3.8 (1.4 to 9.9) 2.3 (0.8 to 6.8) 3.7 (1.5 to 8.7) 1.8 (0.7 to 4.5) 3.2 (0.9 to 10.8) 1.0 (ref)
Aggressivity†† 4.2 (1.7 to 10.3) 1.7 (0.6 to 5.1) 2.2 (0.9 to 5.5) 1.2 (0.5 to 3.3) 2.8 (0.8 to 9.6) 1.0 (ref)
Passivity‡‡ 3.6 (1.1 to 11.5) 1.1 (0.2 to 5.6) 5.1 (1.9 to 13.7) 2.1 (0.7 to 6.3) 4.8 (1.3 to 17.9) 1.0 (ref)
Anxiety§§ 6.0 (1.9 to 18.8) 2.7 (0.7 to 10.5) 4.6 (1.5 to 13.7) 1.4 (0.4 to 5.3) 4.2 (1.0 to 18.4) 1.0 (ref)
Academic learning¶¶ 3.0 (1.2 to 7.5) 0.9 (0.2 to 3.3) 1.6 (0.6 to 4.0) 1.1 (0.4 to 2.9) –*** 1.0 (ref)
Academic performance††† 7.6 (2.5 to 23.1) 2.8 (0.7 to 10.6) 2.6 (0.8 to 8.8) 2.8 (0.9 to 8.7) –*** 1.0 (ref)
Fine motor development‡‡‡ 7.1 (2.5 to 19.9) 1.7 (0.4 to 7.0) 3.4 (1.2 to 9.7) 3.6 (1.3 to 9.9) 3.4 (0.8 to 14.2) 1.0 (ref)
Combined§§§ 3.7 (2.1 to 6.3) 1.3 (0.7 to 2.4) 2.7 (1.6 to 4.3) 1.4 (0.8 to 2.2) 1.7 (0.8 to 3.6) 1.0 (ref)

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