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Arch Dis Child Fetal Neonatal Ed 87:F144-F149 doi:10.1136/fn.87.2.F144
  • Original article

Clinical course and medical management of neonates with severe cardiac failure related to vein of Galen malformation

Table 3

Clinical outcome including magnetic resonance angiography/magnetic resonance imaging demonstration of residual shunt, neurological development, and number of procedures performed in the first year of life

Patient Timing and nature of intervention Duration of ventilation (days)* Length of hospital stay (days) Age at latest follow up (months) Clinical findings Follow up neuroradiology
*Includes nasal continuous positive airway pressure.
TV, Transvenous approach; TA, transarterial approach; TT, transtorcular approach; CPAP, continuous positive airway pressure; CT, computed tomography; MRI, magnetic resonance imaging; AVM, arteriovenous malformation.
1 TV (2 days), TT (6 days), TA (39 days) 15 (25 CPAP) 51 45 Age appropriate development Normal CT MRI at 12 months
2 TA (6 months), TA (7 months), TA (7 months) 1 8 40 Age appropriate development CT scan normal at 22 months
3 TT (2 days) 1 1 0 Died at day 2 Died
4 TV (3 days), TA (13 months), TA 20 months), TA 22 months) 15 32 36 Moderate developmental delay CT scan at 17 months: small R parietotemporal infarct
5 TV (4 days), TA (7 days), TV (13 days), TA (12 months) 14 32 24 Age appropriate development CT scan normal at 12 months; complete obliteration AVM
6 TV+TA (6 days) 5 20 48 Age appropriate development CT scan normal at 24 months
7 TV (1 day), TV (2 days), TV + TT (11 days) 26 26 0 Died at day 24 CT scan at day 17: diffuse anoxic brain injury
8 TV (2 days), TA (6 days), TA (22 days) 7 29 days 10 Age appropriate development MRI normal at 8 months
9 TV (1 day), TA (3 days), TA (8 days), TA (14 days) 14 39 days 1 Died Severe ischaemic cortical injury

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