Endothelin 1 concentrations in infants with meconium stained amniotic fluid
- 1Hacettepe University Hospital, Department of Pediatrics, Division of Neonatology
- 2Social Security Hospital, Ankara
- 3Hacettepe University Hospital, Department of Pediatrics, Division of Haematology
- Correspondence to:
Dr S Yigit, Ziraat Mühendisleri Sitesi 3/21 Çankaya 06550, Ankara, Turkey;
Suleyigit{at}turk.net
- Accepted 17 May 2002
Abstract
Plasma endothelin 1 concentrations were determined in infants with meconium stained amniotic fluid. Plasma endothelin 1 concentration in the study group (5.23 pg/ml) was statistically higher than that in the control group (1.12 pg/ml). Cord blood pH and base excess values were significantly lower in infants with meconium stained amniotic fluid when compared with the control group. There was no correlation between endothelin 1 concentrations and pH or base excess values. Results suggest that meconium passage is not a physiological event, even if meconium stained infants appear to be clinically healthy.
