Iodine deficiency associated with parenteral nutrition in extreme preterm infants
- M Ibrahim1,
- G Morreale de Escobar2,
- T J Visser3,
- S Durán2,
- H van Toor3,
- J Strachan4,
- F L R Williams5,
- R Hume1
- 1Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
- 2Departmento de Endocrinologia, Instituto de Investigaciones Biomedicas “Alberto Sols” Arturo Duperier 4, Spanish Research Council and Autonomous University of Madrid, Madrid 28029, Spain
- 3Department of Internal Medicine III, Erasmus University, University Hospital Dijkzigt, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
- 4Department of Biochemical Medicine, Ninewells Hospital and Medical School
- 5Department of Epidemiology and Public Health, University of Dundee, Ninewells Hospital and Medical School
- Correspondence to:
Professor Hume, Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland UK;
r.hume{at}dundee.ac.uk
- Accepted 19 June 2002
Abstract
Infants are in negative iodine balance on current standard regimens of total parenteral nutrition, with a mean iodine intake of 3 μg/kg/day (150 ml/kg/day). The recommended enteral intake of iodine for preterm infants is 30 μg/kg/day. Gastrointestinal absorption of iodine is high, suggesting that parenteral intakes should approach enteral recommendations.








