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Arch Dis Child Fetal Neonatal Ed 88:F113-F118 doi:10.1136/fn.88.2.F113
  • Original article

Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding

Table 1

Clinical data and laboratory values at admission in the two groups

Oral group Intravenous group
Results are expressed as median (range).
*p=0.038, **p=0.034 compared with oral group. There were no significant differences between the two groups with respect to the other variables.
No of babies 24 20
Sex (% male) 54.2 70.0
Gestational age (weeks) 39 (35–42) 37 (28–41)*
Birth weight (g) 3000 (900–4200) 2500 (900–3400)**
Age at time of study (weeks) 6.0 (1–26) 6.5 (1–12)
Weight at time of study (kg) 3.8 (1.8–5.7) 3.2 (1.7–5.0)
No. less than 10th centile for weight 15 (56%) 16 (80%)
Serum bilirubin (normal, 3–20 μmol/l) 136 (46–438) 153 (36–288)
Aspartate aminotransferase (10–50 IU/l) 140 (32–1768) 168 (23–558)
Alkaline phosphatase (30–150 IU/l) 484 (213–893) 602 (214–1853)
γ Glutamyl transferase (5–55 IU/l) 175 (30–1073) 298 (15–1830)
International normalised ratio (0.7–1.2) 0.90 (0.76–1.17) 0.90 (0.74–1.08)

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