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Arch Dis Child Fetal Neonatal Ed 88:F223-F228 doi:10.1136/fn.88.3.F223
  • Original article

Cardiac output, pulmonary artery pressure, and patent ductus arteriosus during therapeutic cooling after global hypoxia-ischaemia

Table 2

Measured and calculated cardiac variables from the experimental pigs (17 normothermic (NT) and 18 hypothermic (HT))

Baseline (n=35) 3 h (n=35) 24 h (n=35) 30 h (n=34) 48 h (n=31)
NT HT NT HT NT HT NT HT NT HT
Values are mean (SD).
*Tricuspid regurgitation velocity evaluated in 27 animals.
MV, Mitral valve velocity; TV, tricuspid valve velocity; PV, pulmonary valve velocity; AV, aortic valve velocity; CO, cardiac output; TR, tricuspid regurgitation velocity; HR, heart rate; MABP, mean arterial blood pressure.
Aorta diameter (mm) 5.9 (0.23) 5.6 (0.6) 5.9 (0.24) 5.7 (0.61) 6.0 (0.24) 5.6 (0.59) 6.0 (0.23) 5.6 (0.59) 6.0 (0.24) 5.7 (0.6)
MV (m/s) 0.76 (0.14) 0.76 (0.17) 0.86 (0.12) 0.92 (0.19) 0.79 (0.12) 0.75 (0.11) 0.74 (0.11) 0.74 (0.12) 0.74 (0.16) 0.69 (0.08)
TV (m/s) 0.62 (0.08) 0.62 (0.11) 0.71 (0.14) 0.75 (0.11) 0.60 (0.15) 0.63 (0.12) 0.54 (0.09) 0.58 (0.10) 0.55 (0.10) 0.56 (0.11)
PV (m/s) 0.96 (0.19) 0.97 (0.18) 1.04 (0.14) 0.98 (0.13) 0.91 (0.17) 0.92 (0.18) 0.89 (0.15) 0.99 (0.21) 0.89 (0.17) 0.95 (0.20)
AV (m/s) 1.2 (0.17) 1.1 (0.21) 1.2 (0.17) 1.0 (0.14) 1.2 (0.19) 1.0 (0.19) 1.2 (0.17) 1.2 (0.17) 1.2 (0.22) 1.2 (0.15)
Stroke volume (ml) 1.97 (0.37) 1.82 (0.35) 2.06 (0.51) 2.11 (0.41) 1.89 (0.41) 1.85 (0.34) 1.88 (0.39) 1.98 (0.35) 1.80 (0.31) 2.03 (0.38)
CO (litres/kg/min) 0.38 (0.06) 0.37 (0.09) 0.41 (0.08) 0.43 (0.09) 0.34 (0.08) 0.30 (0.08) 0.35 (0.08) 0.33 (0.06) 0.32 (0.09) 0.30 (0.08)
TR* (m/s) 3.1 (0.34) 3.0 (0.49) 3.4 (0.42) 3.0 (0.45) 3.0 (0.27) 3.0 (0.42) 3.0 (0.31) 3.1 (0.38) 2.9 (0.35) 2.9 (0.23)
HR (beats/min) 194 (18) 184 (29) 202 (32) 197 (23) 187 (35) 166 (35) 172 (36) 173 (30) 169 (35) 163 (30)
MABP (mm Hg) 61 (9.9) 55 (7.4) 75 (11.0) 80 (15.1) 66 (13.7) 67 (11.9) 68 (12.4) 63 (15.5) 66 (11.5) 72 (15.5)

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