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Arch Dis Child Fetal Neonatal Ed 2003;88:F446 doi:10.1136/fn.88.5.F446
  • LETTER

Methaemoglobinaemia with concurrent blood isolation of Saccharomyces and Candida

  1. M S Lungarotti,
  2. D Mezzetti,
  3. M Radicioni
  1. Policlinico Monteluce, Via Brunamonti, Perugia, PG 06100, Italy; dm2@unipg.it

      Saccharomyces boulardii is closely related to Saccharomyces cerevisiae and is used as biotherapeutic agent,1 although some reports suggest pathogenicity.2 We present a case of neonatal fungaemia with concurrent methaemoglobinaemia, occurring after a brief period of treatment with S boulardii. A male infant was born at 30 weeks of gestational age by caesarean section because of intrauterine growth restriction and maternal hypertension. The baby was well apart from persistent gastrointestinal symptoms that hampered feeding and forced parenteral support. During the …

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