Tanner, S F; Cornette, L; Ramenghi, L A; Miall, L S; Ridgway, J P; Smith, M A; Levene, M I

Table 1

Clinical details and imaging findings of infants studied

Patient	GA	Age at scanning	Clinical		Imaging findings
Perfusion voids correspond to pixels where the software was unable to calculate values of perfusion; see text.
GA, Gestational age; GM, grey matter; HIE, hypoxic ischaemic injury; ICH, intracranial haemorrhage; C, conventional magnetic resonance imaging, T1 and T2 weighted images; P, perfusion imaging; PHH, post-haemorrhagic hydrocephalus; WM, white matter.
1	25	19 days	PHH	C	Bilateral IVH, left venous infarction, secondary PHH
				P	Perfusion not detected in WM; well characterised in GM
2	34	3 days	HIE injury	C	Bilateral IVH, bilateral venous infarction, cortical highlighting, oedema
				P	Extensive perfusion voids in WM
3	35	3 days	Sialoblastoma	C	Large soft tissue mass without intracranial extension
				P	Small perfusion voids in WM and some in GM
4	37	14 days	Convulsions	C	Normal
				P	Small perfusion voids in WM; perfusion well characterised in GM	Fig 2D
5	38	7 months	Meningococcal meningitis	C	Normal
				P	Perfusion well characterised in GM and WM
6	39	8 days	Convulsions	C	Extensive cortical highlighting and WM oedema
				P	Perfusion well characterised in GM and WM
7	39	23 days	Convulsions	C	Normal
				P	Extensive perfusion voids in WM; perfusion well characterised in GM
8	39	18 months	Di George syndrome	C	Severe hydrocephalus	Fig 1A,C
				P	Perfusion well characterised in GM and WM; voids due to enlarged ventricles hypoxic ischaemic encephalopathy	Fig 1B,D
9	40	2 days	Axial hypotonia	C	Normal
				P	Minimal perfusion voids in WM
10	40	4 days	Disraphysm	C	Several punctate lesions in WM
				P	Minimal perfusion voids in WM
11	40	5 months	Convulsions	C	Slightly prominent lateral ventricles-otherwise normal
				P	Perfusion well characterised in GM and WM
12	41	13 days	HIE injury	C	Extensive and generalised WM oedema	Fig 2A
				P	Perfusion voids in frontal WM and focally in cerebral cortex	Fig 2B
	41	69 days	HIE injury	C	Cystic change in posterior parieto-occipital region; atrophic changes	Fig 2C
				P	Not available

Cerebral perfusion in infants and neonates: preliminary results obtained using dynamic susceptibility contrast enhanced magnetic resonance imaging

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